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Letter from the President               Q309

It has been a time of historical proportions that has changed the markets and industries forever, including both the pharmaceutical and biotechnology sectors. In the midst of all of this activity PhytoMedical continues to persevere with the successful execution of their business strategy. It is from here that I wanted to take this opportunity to provide you with an update on PhytoMedical’s progress these past months. I also welcome you to review our press releases.

The pharmaceutical industry is in the midst of reinventing itself, shifting from the costly strategy of acquiring a defined number of late-stage primary care compounds towards securing a large number of specialized early stage developmental opportunities. This shift bodes well for PhytoMedical as we continue to develop our anti-cancer compounds based upon the science of bis-intercalation.

During 2007-2008 we successfully conducted and completed a series of anti-cancer in vitro studies which justified our action to acquire the worldwide licensing rights from Dartmouth College in late 2008 and subsequently initiate the renewal of our Sponsored Research Agreement. Upon successful completion of the in vitro studies we progressed to the next phase of research initiating two variant in vivo toxicity and efficacy studies which began in late second quarter 2008. We announced in late October 2008 the successful results of the first phase of our anti-cancer in vivo studies specific to colon cancer. The second phase, specific to glioblastoma, began shortly afterwards and was completed in early Q109. Although both tests demonstrated favorable results the researchers reviewed the data collected from these important efficacy and toxicity tests, and surmised that PhytoMedical’s anti-cancer compound(s) may “...have its selectivity in killing SF295 human glioblastoma cells.” Comparatively, broad anti-cancer treatments may be less effective and carry greater risks and side-effects than compounds with the key ability to selectively target and kill specific cancer cells -- an important consideration for the treatment of cancers in vital organs such as the brain, where glioblastoma is exhibited. Given the associated costs and limited successful treatment options for treating glioblastoma, we are excited to be pursuing a selective treatment option for this deadly disease through the expansion of our research efforts. We are currently working on the development of our IV Formulation which is a vital step towards our Investigational New Drug (IND) preparation.

Additional developmental opportunities

PhytoMedical has developed a strong network amongst the pharmaceutical, biotechnology and academic science communities. It is from there that PhytoMedical continues to actively search and review other unique science and future partnerships.

Advisory Board

PhytoMedical’s Advisory Board encompasses an experienced, dynamic group of experts that provides PhytoMedical with the necessary expertise to successfully progress their development in addition to searching and reviewing new opportunities.

Our Future

Given the strong industry network that PhytoMedical possesses we are constantly discussing the developmental progress of our technology with potential partners for future opportunities.

Industry Recognition

We are continually approached by all facets of the industry regarding the recent success of our development. Most recently we were featured in an article in Drug Discovery.

We at PhytoMedical appreciate the continued support and encouragement and look forward to the future of providing successful treatment options for both the patient and physician. Thank you and I encourage you to keep in touch by visiting our website (www.phytomedical.com) and or contacting us directly at 1-800-611-3388.

Regards,

Greg Wujek

President, CEO

 

Legal Notice Regarding Forward-Looking Statements

No statement herein should be considered an offer or a solicitation of an offer for the purchase or sale of any securities. This release contains forward-looking statements that are based upon current expectations or beliefs, as well as a number of assumptions about future events. Although the Company believes that the expectations reflected in the forward-looking statements and the assumptions upon which they are based are reasonable, it can give no assurance that such expectations and assumptions will prove to have been correct. Forward-looking statements, which involve assumptions and describe our future plans, strategies, and expectations, are generally identifiable by use of the words “may,” “will,” “should,” “could,” “expect,” “anticipate,” “estimate,” “believe,” “intend,” or “project” or the negative of these words or other variations on these words or comparable terminology. The reader is cautioned not to put undue reliance on these forward-looking statements, as these statements are subject to numerous factors and uncertainties, including but not limited to adverse economic conditions, intense competition, lack of meaningful research results, entry of new competitors and products, adverse federal, state and local government regulation, inadequate capital, unexpected costs and operating deficits, increases in general and administrative costs, termination of contracts or agreements, technological obsolescence of the Company's products, technical problems with the Company's research and products, price increases for supplies and components, litigation and administrative proceedings involving the Company, the possible acquisition of new businesses or technologies that result in operating losses or that do not perform as anticipated, unanticipated losses, the possible fluctuation and volatility of the Company's operating results, financial condition and stock price, losses incurred in litigating and settling cases, dilution in the Company's ownership of its business, adverse publicity and news coverage, inability to carry out research, development and commercialization plans, loss or retirement of key executives and research scientists, changes in interest rates, inflationary factors, and other specific risks. We currently have no commercial products intended to diagnose, treat, prevent or cure any disease. The statements contained in this press release regarding our on going research and development and the results attained by us to-date have not been evaluated by the Food and Drug Administration. There can be no assurance that further research and development, and /or whether clinical trial results, if any, will validate and support the results of our preliminary research and studies. Further, there can be no assurance that the necessary regulatory approvals will be obtained or that PhytoMedical will be able to develop commercially viable products on the basis of its technologies. In addition, other factors that could cause actual results to differ materially are discussed in the Company's most recent Form 10-QSB and Form 10-KSB filings with the Securities and Exchange Commission. These reports and filings may be inspected and copied at the Public Reference Room maintained by the U.S. Securities & Exchange Commission at 100 F Street, N.E., Washington, D.C. 20549. You can obtain information about operation of the Public Reference Room by calling the U.S. Securities & Exchange Commission at 1-800-SEC-0330. The U.S. Securities & Exchange Commission also maintains an Internet site that contains reports, proxy and information statements, and other information regarding issuers that file electronically with the U.S. Securities & Exchange Commission at http://www.sec.gov. The Company undertakes no obligation to publicly release the results of any revisions to these forward looking statements that may be made to reflect the events or circumstances after the date hereof or to reflect the occurrence of unanticipated events.



 

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